Methyl 2-chloro-5-(trifluoromethyl)isonicotinate

Methyl 2-chloro-5-(trifluoromethyl)isonicotinate - Names and Identifiers

Name	Methyl 2-chloro-5-(trifluoromethyl)isonicotinate
Synonyms	Methyl 2-chloro-5-(trifluoromethyl)isonicotinate 2-Chloro-4-(methoxycarbonyl)-5-(trifluoromethyl)pyridine Methyl 2-chloro-5-(trifluoroMethyl)pyridine-4-carboxylate Methyl 2-chloro-5-(trifluoromethyl)pyridine-4-carboxylate 2-chloro-5-(trifluoroMethyl)isonicotinic acid Methyl ester 2-chloro-5-(trifluoromethyl)isonicotinic acid methyl ester 4-Pyridinecarboxylic acid, 2-chloro-5-(trifluoromethyl)-, methyl ester Methyl 2-chloro-5-(trifluoromethyl)pyridine-4-carboxylate, 2-Chloro-4-(methoxycarbonyl)-5-(trifluoromethyl)pyridine
CAS	1246685-28-8
InChI	InChI=1S/C8H5ClF3NO2/c1-15-7(14)4-2-6(9)13-3-5(4)8(10,11)12/h2-3H,1H3

Methyl 2-chloro-5-(trifluoromethyl)isonicotinate - Physico-chemical Properties

Molecular Formula	C8H5ClF3NO2
Molar Mass	239.58
Density	1.443±0.06 g/cm3(Predicted)
Boling Point	278.5±40.0 °C(Predicted)
pKa	-3.87±0.10(Predicted)
Storage Condition	Room Temprature

Methyl 2-chloro-5-(trifluoromethyl)isonicotinate - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29333990

Methyl 2-chloro-5-(trifluoromethyl)isonicotinate - Introduction

2-Chloro-5-trifluoromethylisonicotinic acid methyl ester is an organic compound with the chemical formula C8H4ClF3O2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
2-Chloro-5-trifluoromethylisonicotinic acid methyl ester is a colorless liquid with a pungent odor. It has a density of 1.534g/cm³, a boiling point of 150°C and a flash point of 28°C. It is a flammable liquid and easily burns when it encounters a fire source.

Use:
2-Chloro-5-trifluoromethylisonicotinic acid methyl ester is commonly used as an intermediate for insecticides, fungicides and herbicides. It is widely used in agriculture and horticulture to control weeds and pests. In addition, it can also be used as dyes, fluorescent whitening agents, pharmaceutical intermediates, etc.

Preparation Method:
2-Chloro-5-trifluoromethyl isonicotinic acid methyl ester can be prepared by reacting 2-chloro-5-trifluoromethyl isonicotinic acid with methanol. The specific step is to react 2-chloro-5-trifluoromethylisonicotinic acid with excess methanol at an appropriate temperature and pressure to produce 2-chloro-5-trifluoromethylisonicotinic acid methyl ester.

Safety Information:
2-Chloro-5-trifluoromethylisonicotinic acid methyl ester is an organic compound with certain toxicity and irritation. Wear protective gloves, protective goggles and protective masks during use or handling to avoid direct contact with skin, eyes and respiratory tract. It is a flammable substance and should be avoided from fire and high temperatures. During storage and handling, attention should be paid to sun protection and moisture protection, and avoid contact with oxidants and strong acids. If it is accidentally leaked or ingested, the affected area should be cleaned promptly and seek medical treatment.

Last Update：2024-04-09 02:00:41